منابع مشابه
Defects in the COG complex and COG-related trafficking regulators affect neuronal Golgi function
The Conserved Oligomeric Golgi (COG) complex is an evolutionarily conserved hetero-octameric protein complex that has been proposed to organize vesicle tethering at the Golgi apparatus. Defects in seven of the eight COG subunits are linked to Congenital Disorders of Glycosylation (CDG)-type II, a family of rare diseases involving misregulation of protein glycosylation, alterations in Golgi stru...
متن کاملBirth defects
Five years before Charles Darwin’s death, the issue of human population growth, which had triggered Darwin’s thoughts on natural selection throughout other species, hit the news with some force. Thomas Malthus, almost a century earlier had raised the fear that uncontrolled human population growth was unsustainable and would be challenged. And in 1877, news was spreading around the world of appa...
متن کاملPrenatal Nutrition and Birth Defects
Evidence of human birth defects dating back over three thousand years is reported in archeological literature. Excavated ruins of ancient Babylon revealed detailed reports of infant defects.1 Achondroplastic dwarfs (failure to develop healthy cartilage at the ends of the long bones, resulting in a form of congenital dwarfism) have been unearthed in ancient Egyptian tombs. Pictures drawn on anci...
متن کاملChromosomal defects and caesarean birth.
The definition of colic was stated in the introductory lines; the healthy babies had expressed colic of three to 13 hours' duration daily, only cases 2 and 6 occasionally having had daily colic of shorter duration than three hours: washout periods have no relevance in this context: any food between treatments might produce carry over effect; professional statisticians were consulted about prope...
متن کاملBirth Defects: Risks and Consequences
included a review of some notable empirical evidence, analyzed and related in a wellthought out epidemiologic fashion. While the text is necessarily complex in parts, its appeal should not be limited; there is something in it to interest everyone. Perhaps a more rational and less zealous attitude concerning the use of marijuana, and its impact on us all, will accompany a widespread reading of t...
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ژورنال
عنوان ژورنال: Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
سال: 2009
ISSN: 0925-4439
DOI: 10.1016/j.bbadis.2008.10.020